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Share on PinterestWegovy is a man-made version the a gut hormone that suppresses hunger and also appetite and is the very first drug the FDA has approved for load loss because 2014. Getty Images
The FDA has approved the medicine Wegovy, a higher dose of the diabetes drug semaglutide, come be provided as a weight management drug in patients through obesity.

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In clinical trials, participants without diabetes who took Wegovy lost an median of 12.4 percent of their initial human body weight.The medicine is a man-made version of a gut hormone the suppresses hunger and appetite.A diabetes drug has actually received approval native the Food and also Drug administration (FDA) to also be offered as a weight-loss medication in patients v obesity.

The medication, Wegovy, is a higher dose of the diabetes medicine semaglutide developed by Novo Nordisk.

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It’s the first drug because that chronic weight management that has been approved by the FDA because 2014.

Wegovy, administered via a once-weekly injection, is suggested for human being with a human body mass index (BMI) of 27 kg/m2 or greater and who have actually at the very least one weight-related medical condition such together high blood pressure or high cholesterol. The medicine is additionally for world who have actually a BMI that 30 kg/m2 or higher.

In the united States, roughly 1 in 3 adult — end 100 million people — have actually obesity. Treating obesity deserve to improve blood pressure, blood sugar, and also cholesterol levels.

“Today’s approval supplies adults with excessive weight or overweight a beneficial new treatment alternative to incorporate into a weight administration program,” Dr. John Sharretts, the deputy manager of the department of Diabetes, Lipid Disorders, and Obesity in the FDA’s facility for medicine Evaluation and also Research, stated in a statement.


Wegovy is a synthetic version the a hormone in the gut, glucagon-like peptide-1, that affects the components of the mind that regulate hunger and also appetite.

It is injected under the skin as soon as a week.

“It slow emptying the the stomach. It disclosure the emotion of fullness (satiety) by exhilaration on the brain, an especially at the level of the hypothalamus,” claimed Dr. Aleem Kanji, a board-certified endocrinologist and obesity medication physician through Ethos Endocrinology in Houston.

In clinical trials assessing the safety and efficacy the Wegovy for load loss, participants there is no diabetes that took Wegovy lost, top top average, 12.4 percent of your initial body weight compared to those who obtained a placebo.

In a clinical trial performed in human being with form 2 diabetes, those who took Wegovy shed 6.2 percent of your body weight contrasted to those who got a placebo.

Those that took Wegovy lost weight steadily because that 16 months before plateauing.

Gastrointestinal worries — diarrhea, vomiting, constipation, abdominal pain, indigestion, flatulence — were frequently reported next effects. These next effects commonly resolved on your own, yet 5 percent the participants stopped taking the medication because of them.

Other participants reported headache, fatigue, and also dizziness.

“Individuals with excessive weight and form 2 diabetes space likely great candidates for the double benefit of enhanced blood sugar control and weight loss,” claimed Kanji.

According to Kanji, data says Wegovy has a favorable safety profile contrasted to older weight loss medications.


Wegovy must not be used with other drugs provided for load loss or medications that contain semaglutide, follow to the FDA.

Wegovy has a potential threat of thyroid C-cell tumors and should additionally not be provided to world with a an individual or family history of medullary thyroid carcinoma and Multiple Endocrine Neoplasia syndrome form 2 (MEN 2).

The drug has not to be studied in people who have actually a history of pancreatitis.

The drug, in ~ a sheep of 1 mg, was first approved for type 2 diabetes in 2017.

Kanji plan to add Wegovy together a treatment option for particular patients with excessive weight — especially those with kind 2 diabetes.

The price is meant to be comparable to Saxenda, which expenses $1,349 a month there is no insurance.

“As is regularly the case, cost and health insurance money coverage will certainly be the limiting factor,” stated Kanji.